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Which of the following statements is true of using folic acid for treating anemias?


A) Folic acid cannot be used to reverse the production of the megaloblastic cells associated with cobalamin deficiency.
B) Folic acid can be used to treat aplastic anemia.
C) Folic acid should never be given for treatment of cobalamin (vitamin B12) deficiency anemia.
D) Folic acid is effective in the treatment of normocytic anemias.

E) B) and D)
F) None of the above

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People suffering from pernicious anemia should:


A) be given 1 mcg of cobalamin orally every day.
B) be given an injection of about 100 mcg of cobalamin every month.
C) be given 100 mcg of cobalamin intravenously on a daily basis.
D) be given 500 mcg of cobalamin intravenously once a month.

E) All of the above
F) A) and B)

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_____ has the longest half-life of all erythropoietin stimulating agents (ESAs) .


A) Aranesp
B) Epogen
C) MIRCERA
D) Procrit

E) A) and B)
F) B) and D)

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Which of the following statements is not true about erythropoietin?


A) Erythropoietin is an enzyme produced in the liver that is necessary for carrying out the metabolic processes of the body's cells.
B) Erythropoietin stimulates the production of red blood cells in the bone marrow.
C) Erythropoietin production is impaired in patients with chronic renal failure.
D) Erythropoietin, in general, should not be added to any other drug solution.

E) None of the above
F) B) and D)

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How can anemia resulting from altered RBC production or from increased RBC destruction be best treated?


A) By replacing iron or cyanocobalamin in the diet
B) By replacing iron or copper through supplements
C) By giving a blood transfusion
D) All of the above

E) B) and C)
F) A) and D)

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_____ are characterized by unusually small red blood cells (RBCs) .


A) Macrocytic anemias
B) Megaloblastic anemias
C) Microcytic anemias
D) Normochromic anemias

E) None of the above
F) A) and B)

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Allison,a teacher at a school for underprivileged children,notices that one of her students,8-year-old Sarah,has an abnormal eating disorder.She often observes Sarah eating clay and chalk.When this habit continues in spite of intervention,Allison takes Sarah to Dr.Ford's clinic for a medical checkup.In addition to pale skin and rapid breathing,Dr.Ford notes that Sarah has abnormally low levels of iron in her blood stream.Based on the information provided in this scenario,Sarah shows the characteristic symptoms of _____.


A) scurvy
B) pica
C) hypokalemia
D) hemochromatosis

E) A) and B)
F) All of the above

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In the context of treating iron deficiency,which of the following is true of ferumoxytol (Feraheme) ?


A) Feraheme is a novel iron product that is supplied as capsules for oral administration.
B) Feraheme is specifically formulated for iron deficiency anemia in patients with chronic kidney disease.
C) Feraheme should be administered as a diluted intravenous injection.
D) Feraheme should only be used in patients for whom gastrointestinal (GI) absorption is impaired.

E) All of the above
F) A) and B)

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Which of the following special considerations should a health-care professional keep in mind while using erythropoietin?


A) Preparations of erythropoietin cannot be frozen or vigorously shaken.
B) Erythropoietin should not be added to any other drug solution.
C) Benzyl alcohol 0.9 percent may be added to the erythropoietin to act as a bacteriostatic agent.
D) All of these are correct.

E) None of the above
F) A) and D)

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David works as a health-care professional at Silver Oak Nursing Home.He is instructed to tend to Alisha Pavel,an undernutritioned patient who has been admitted at the nursing home for treatment.Which of the following instructions should David give Alisha when she is taking her oral hematinics?


A) Do not take the supplements on an empty stomach.
B) Chew or crush the supplements prior to swallowing.
C) Take liquid iron preparations with juice or water.
D) Always take antacids simultaneously with oral iron supplements.

E) A) and C)
F) A) and B)

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_____ is a protein normally produced by the kidneys that participates in red blood cell homeostasis.


A) Intrinsic factor
B) Erythropoietin
C) Transcobalamin II
D) Transferrin

E) A) and B)
F) A) and C)

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Which of the following statements is true of iron intake by the body?


A) After age 20, healthy males require more iron intake than do females.
B) The recommended dietary allowance (RDA) for iron should be between 10 and 18 mg.
C) Strict vegetarians are less likely to develop a dietary deficiency of iron.
D) The amount of iron in the body is maintained at a relatively constant level between 15 and 20 g

E) All of the above
F) C) and D)

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Which of the following is true of intrinsic factor?


A) Intrinsic factor is a glycoprotein that is necessary for the intestinal absorption of vitamin B12.
B) Intrinsic factor is an enzyme that is necessary for the metabolism of vitamin B12.
C) The lack of intrinsic factor leads to a microcytic hypochromic type of anemia.
D) None of these are correct.

E) A) and B)
F) A) and C)

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_____ is caused by the defective functioning of the blood-forming organs (bone marrow) .


A) Aplastic anemia
B) Normocytic anemia
C) Pernicious anemia
D) Sickle cell anemia

E) A) and B)
F) A) and C)

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Which of the following is true of the various types of anemia?


A) In deficiency anemia, where there is a lack of iron or lack of copper, the RBCs are microcytic hypochromic.
B) In deficiency anemia, where there is a lack of iron or lack of copper, the RBCs are normocytic normochromic.
C) In deficiency anemia, where there is a lack of iron or lack of copper, the RBCs are sickle-shaped microcytic.
D) None of these are correct.

E) B) and D)
F) B) and C)

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